Archive

Posts Tagged ‘Arteries’

Dec
26

When that inspired individual invented the wheel in those distant centuries, there was no patent system to protect the novelty of the idea. Everyone else looked on as the first wheels appeared on the streets and, before you could say, Jack Robinson, everyone had wheels. Those were the days when everyone shared the benefits of all the inventions. Times were hard and survival mattered more than commercial intellectual property rights. It took a long time for the world to come round to the view that inventions should be subject to a monopoly protection. We had a fully developed market economy back in Ancient Greece and Rome. There was a universal currency throughout both political groups, but it was not until a few hundred years ago that aggressive merchants began to buy monopoly rights from the political rulers. Now, we seem to take it as given that anyone who creates something new should have protection. Except, that is, when it comes to downloading the odd copyright-protected MP3.

In theory, this should not cause too many problems except the patent system is used to stifle creativity and keep out competing products while the patent holder changes the maximum possible retail price. This penalizes us, the consumers. We either pay the asking price or go without. So welcome to the court of District Judge Rebecca Beach Smith. Note it fell to a woman to decide the fate of men as we all waited for cheaper erectile dysfunction drugs. So here comes an international company with the nerve to threaten the cosy US market with cheap generic drugs. This competition on price would have affected the three current patent holders. Pfizer took the lead and argued it had a patent up to 2019.

Why so long? Well, after patenting the underlying chemistry as a treatment for high blood pressure in the arteries running through the chest and lungs, it registered a second patent for the same drug as a treatment for erectile dysfunction. Check out the history. You’ll find the erectile dysfunction use of the drug was an accidental discovery during the trial for hypertension. The foreigners were bold, arguing this was nothing new. It was obvious from the first research trial. Unfortunately, the judge disagreed and ordered the foreigner to take its cheap generics away and not return until 2019. This means we continue to suffer the price gouging from all three manufacturers with no immediate sign of there being anyone able to introduce a generic into the market.

Have you noticed how aggressive the manufacturers are when advising us not to buy our drugs online. The problem for them is that almost all the major online pharmacies are based overseas where generics are freely available. If you check out these pharmacies, you almost always find the cheap generics available. So, for erectile dysfunction, you can usually make real savings on your supplies of Cialis, even after adding in the cost of shipping. The only danger comes from the laws of some US states which mandate customs to confiscate imported drugs for which there’s no valid prescription. So, before you order your Cialis online, check out your local laws on importation. The packages always come in plain wrappers so there’s always a good chance they will get through undetected.

, , , , , , , , , , , , , , , , , , ,

May
03

Disease can’t be good or bad. Sometimes, you can be grateful a particular problem is not terribly serious. Other times, it’s just your bad luck you were the one to catch the particular disease. Yet, some disorders are rightly considered unfair. Among these are several variations on muscular dystrophy. Indeed, any disorder that comes courtesy of your genes is unfair. You can blame yourself for stupidity if you go into the jungle without taking your shots against the local diseases.

But if your disorder is an accident of the way your parents’ genes came together at conception, it’s not your fault. All you can do is make the best of a bad job. The muscular distrophies are a form of wasting disease. They are progressive and slowly break down the tone and control of muscles. At first, this leads to weakness and bad co-ordination. As the disorder progresses, sufferers are restricted to wheelchairs and their general health is affected. At present, there’s no cure, but people can slow down the effects by exercising regularly to strengthen the musculature.

A team is working at the Cedars-Sinai Medical Center in California. The research interest is in the Becker variant of muscular dystrophy which almost exclusively affects men and always affects sexual performance. A small, double-blind, placebo-controlled trial is proceeding to test the effect of tadalafil. There is good evidence to show the use of erectile dysfunction drugs dilates the arteries and improves the flow of oxygen-rich blood to the muscles during exercise.

Indeed, sporting authorities around the world are increasingly concerned that men who use these medications as a part of their training regimes may gain an unfair advantage when they compete. Tests are underway to decide whether their use should be banned in the Olympics and other major sporting events. In studies using mice training with erectile dysfunction drugs, the results show the mice were able to exercise more vigorously with less risk of damage to their muscles. If a part of the cause of muscle weakness among those with muscular dystrophy is poor blood supply, the use of erectile dysfunction drugs would seem indicated to improve the ability of the men to exercise for longer periods of time.

This research is at an early stage but the ability of cialis to dilate arteries in different parts of the body is now the subject of quite different FDA approvals for the treatment of erectile dysfunction and pulmonary arterial hypertension which causes severe pain in the chest. With this diversification an established fact, it will be interesting to see how these men with muscular dystrophy react to cialis. If the results are sufficiently encouraging, we could well see a major clinical trial launched in 2011 to see whether the results scale up to a statistically significant number of men. Being honest and optimistic, we hope to be able to report significant benefit to those who suffer from muscular dystrophy. Although this will not represent a cure – until scientists develop a way of repairing defective genes, no cure is possible – it may well slow the progression of the disorder and improve the quality of life.

, , , , , , , , , , , , , , , , , , ,

May
01

It’s a sad fact of life that much of the research published in the medical journals is depressing. These scientists spend their lives studying all the different ways in which people can die. There are only a few major breakthroughs each year. The rest of the time, the best you can hope for is a small step forward in understanding the problems. In the case of erectile dysfunction (ED) there is a clear trend emerging. In England, Dr Kirby who recently published Sleeping With Ed, has been co-ordinating research into the relationship between men with ED and cardiovascular disease. The current state of the research shows that the first symptoms of ED double the risk of developing heart disease within four years. The reason is easy to state. The usual physical reason for ED is that the artery leading into the penis does not dilate properly. This is a narrow artery. If there is a problem with this artery now, the same problem is likely to affect the larger arteries in the chest and lungs next. ED is a better predictor of heart disease than high cholesterol, high blood pressure or among smokers. The next phase of the research is to begin treating men with drugs to lower the levels of lipids and statins to see whether fewer cases of heart disease emerge. But in the UK, many doctors continue to view ED as a problem of lifestyle and not as the basis of predicting more serious health problems.

In the US, the Mayo Clinic has recently published an important new study demonstrating that heart disease can be slowed or halted by early medical intervention. This means treating all younger men between 40 and 49 who consult their doctors with ED as potential heart patients. So, when you go see your doctor about ED, do not be surprised if a range of tests for heart disease are ordered. For the record, between 5 and 10% of men under 40 are likely to experience ED. It then becomes increasingly common as men age. Between 40 and 60% of men over 70 are affected.

So, this research is good news for two reasons. The first is that, having proved the link, it is now possible to prevent the early deaths of many younger men from strokes or heart attacks. Drugs to reduce blood pressure and cholesterol levels, improved diet and exercise combine in a regime to extend lives. All this is possible because you experience ED. The second reason is that levitra will offer immediate relief to the problem of ED. However, you should not buy levitra on the internet and self-medicate. You need careful guidance on dosage if you do start taking other drugs to control your blood pressure. That said, with proper guidance, there is no reason why, with levitra, you should not cure the ED, and live a longer and more satisfying life as a result.

, , , , , , , , , , , , , , , , , , ,

Apr
01

Whenever you start reading about erectile dysfunction, the first facts that leap off the screen are that this is a physical problem and, as such, there is a treatment or cure. Most of the explanations of why erections fail focus on different chemical messengers, and arteries dilating or contracting. It’s like reading a description of a plumbing system – turn this valve, water pressure builds here, and so on. This type of explanation suits the pharmaceutical companies. If this chemical messenger is the problem, a drug that specifically targets it will solve the problem. Except human biology is not always so predictable. Let’s start again. From the dawn of time, men have sometimes had difficulty in getting an erection hard enough to penetrate a woman. Out of frustration, they have looked around for solutions and, over time, a number of natural substances have emerged as aphrodisiacs. The lists vary from century to century and culture to culture. The substances work because the prevailing mythology predicts they will work. It may be the crushed horn of this animal added to food, or the blood of this animal notorious for its sexual prowess rubbed on to your penis. There are no common denominators. The process that produces the results takes place in the mind. These substances work because the mind believes in them strongly enough.

Starting this article again means making a simple statement. An erection is a response to sexual stimulation. If the mind does not find the activity stimulating, there will be no erection. As proof of this, we need go no further than the thousands of clinical trials for all major drugs on the market. The methods are consistent. You divide the participants into two groups. One gets the real drug. The other gets a placebo, i.e. a fake tablet that looks the same but is made out of chalk or some other inert substance. A placebo cannot have any physical effect but, on average, about one-third of all participants who are given the placebo report an improvement in their condition. They improve because the mind is strong enough to change the biology of the body.

Now we can say something real about a drug like cialis. This is the leading brand for the treatment of erectile dysfunction in many of the markets around the world. It’s reputation is so great that it has even attracted the nickname of the “weekend pill”, i.e. it produces thirty-six hours of sexual responsiveness. There is no doubt at all about the effectiveness of this drug. As a matter of chemistry, it does exactly what it’s supposed to do. What completes its performance is the power of its reputation. When men take a drug which has such a good reputation, the chemical action is added to the placebo effect and, with mind and body working together, it produces the best results. Cialis is good and gets better because men believe in it. Now available in two forms, you can enjoy the benefits of this modern aphrodisiac as either the weekend pill, taken as needed, or in a once-daily form to give you an erection on demand whenever the opportunity arises.

, , , , , , , , , , , , , , , , , , ,

Mar
29

High Blood pressure treatment

Most of us know Sildenafil as the medicine that treats erectile dysfunction. Only few of us know that this drug can also treat angina and any other chest problems that may occur.

This medical substance is used for preventing or partially decreasing the rate of a chemical reaction – that chemical that could be found in some of the body parts, mainly where PDE is found. The blood pressure is the major obstacle to go through therefore the goal of the Sildenafil experience is to hit the arteries in the lungs as exactly the lungs should have the blood pressure decreased.

Many counties went on with the researches on Sildenafil, trying to figure out what other benefits it gives to people that take it. High Blood pressure treatment seemed to be one of those. The drug ended up being approved by the government and started to get manufactured under a completely different name – known as Revatio. The bets thing about it is that it only penetrates in the arteries where the high blood pressure exists and doesn’t go though all the vascular system. Some kids are born with pulmonary arterial hypertension so there have been some cases when Sildenafil was given to kids for an experiment. The drug makes the blood circulate more actively running through the baby chest. But you have to remember that the dose should not be big as it is a child and their body is much different from an adult body. We have to warn you that the drug is only good when taken rationally as an overdose can create the health problems that have not been predicted before.

Sportsmen praise the drug.

You may never believe it or even find it funny to believe but many famous sportsmen have admitted that Sildenafil is very useful when it comes to making a great performance on the field. This fact has no FDA approval and there is no guarantee that it actually does magic in sports. We have a word of one of the widely renowned sportsmen such as Roger Clemens and others that are ready to confess all around the world how worthy Viagra is for sport result achievements. The good thing about the medication is that it is actually not considered to be an enhancing drug that can influence the body in the wrong way. It is just created to make the circulation better and that is not banned anyhow anywhere. The body gets much stronger and works much better with this drug. But of course, the dosage should be regular as getting a bigger does leads to unpredictable consequences.

A way of curing the high-altitude pulmonary edema

Some institutions claim that Viagra’s dose may help you get on the path of recovery. When we talk about pulmonary edema – we get frightened, as the outcome of this malady can be as severe as death. But Sildenafil (generic viagra) can reduce the altitude and make the illness less harmful. Scientists from Nepal made this discovery not so long ago and they are now almost 100% sure that the drug lets the patients have the ability to absorb oxygen. For those people who need an urgent hospitalization it is the best salvation as sometimes patients happen to live far away and it take time to transport them to the hospital.

Now you know the magic tricks Sildenafil is capable of doing. I hope you know to use it when you have to!

, , , , , , , , , , , , , , , , , , ,